Stressrelaterte genuttrykks- og proteinutrykksforandringer i ulike kroppsvæsker ved ulike former for fysisk og psykisk stress (tidligere godkjent REK-søknad ref. nr. 082.06).

Prosjektsamandrag

Main goals: 1. Optimal sleep and daily rhythms is important for lowest possible cell stress in all projects and will be monitored when possible also as an important part of general optimal pre-analytical conditions strictly followed and after already ethical approved protocols. 2. Blood serum and ev. saliva sampling period is only 48 hours total, one control-day and night and one test-day and night. In addition, tissue samples from animal model will be done after ethically already approved protocols. 3. All projects have a stress-component where we look for changes in the same/common stress-related proteins as well as changed protein profile, the mostly changed proteins and try to ID them. All data will be analyzed in a similar chemical and bioinformatic way both separately in each distinct stress-phenotype project and if possible collapsed as a whole dataset from all or several different stressful conditions to easier localize common biomarkers for different stress-phenotypes. 4.

Metode

Kvantitative analysemetoder, Kvalitative analysemetoder